4 days agoNewcastle fullback Jetro Willems: We ran Chelsea close

first_imgAbout the authorPaul VegasShare the loveHave your say Newcastle fullback Jetro Willems: We ran Chelsea closeby Paul Vegas4 days agoSend to a friendShare the loveNewcastle United fullback Jetro Willems has urged teammates to stay calm after their 1-0 loss at Chelsea.The narrow defeat plunged the Magpies back into the relegation zone and piled the pressure back on the team ahead of next weekend’s tough encounter with Wolverhampton Wanderers at St James’ Park.Willems said: “It was close. I think we had the game under control and we were a little bit unlucky.”If it wasn’t for the goal I think we did good defensively – they have a good team and they are difficult players to play against.”Attacking, we could do more.”In the first half, we could have been more dangerous on the counter attack.”We had some chances – sometimes we were unlucky, but sometimes I think we need to just shoot when we are in front of goal.” last_img read more

‘Boots to the Street’ Goes to St. Thomas

first_imgThe Ministry of Finance and the Public Service continues its ‘Boots to the Street’ community sensitisation sessions on Friday (July 20) at the Paul Bogle High School Resource Centre in St Thomas, beginning at 9:00 a.m.The islandwide initiative was developed by the Ministry’s Communication and Public Relations branch in an effort to raise greater awareness about the work of the entity.Director of Communication and Public Relations in the Ministry, Elaine Oxamendi Vicet, told JIS News that this round of the initiative is targeted at youth aged 19 to 35.She informed that the Scholarship Unit will be joining the team in St. Thomas.“The representatives will be talking to persons about scholarship opportunities available at the Ministry and how to access them,” she said.The team will also be providing information regarding business and financial matters, while highlighting the role of each citizen in helping the country to achieve its economic goals.The ‘Boots to the Street’ programme, which began in 2015, takes the form of a ‘corner-side chat’ with citizens on the street or a town hall meeting.last_img read more

39B buyout of Tribune by Sinclair ends in acrimony

first_imgNEW YORK, N.Y. – The $3.9 billion buyout of Tribune Media by Sinclair collapsed Thursday, ending a bid to create a massive media juggernaut that could have rivaled the reach of Fox News.Tribune Media Co. said Thursday that it is suing Sinclair for breach of contract and at least $1 billion in damages, according to its complaint .Sinclair used “unnecessarily aggressive and protracted negotiations” with the Department of Justice and Federal Communications Commission over regulatory requirements, the Chicago company said, and it refused to sell the stations it needed to in order to gain regulatory approval.Sinclair Broadcast Group wanted the Chicago company’s 42 TV stations and had initially agreed to dump almost two dozen of its own to score approval by the FCC.The media company, which has enjoyed the support of President Donald Trump, appeared to be cruising toward approval by U.S. regulators.Last month, however, FCC Chairman Ajit Pai said that he had “serious concerns” about the deal, saying that Sinclair might still be able to operate the stations “in practice, even if not in name.”That drew a rebuke from Trump.“So sad and unfair that the FCC wouldn’t approve the Sinclair Broadcast merger with Tribune,” Trump tweeted. He said that allowing Sinclair to expand its reach would have led to a “much needed conservative voice by and for the people.”Sinclair operates 192 stations, runs 611 channels and operates in 89 U.S. markets. It would have been able to expand rapidly into numerous new markets with the Tribune acquisition.Sinclair has become a significant outlet for conservative views.It was admonished by media watchdogs in April after Deadspin, a sports news site, pieced together clips of dozens of TV anchors for Sinclair reading from the same script, which warned viewers about “biased and false news” from other media outlets.Sinclair has defended the decision to have its anchors read from the same script across the country as a way to distinguish its news shows from unreliable stories on social media.The Maryland company said Thursday in a prepared statement that the Tribune lawsuit is “entirely without merit.”“We unequivocally stand by our position that we did not mislead the FCC with respect to the transaction or act in any way other than with complete candour and transparency,” said CEO Chris Ripley.Free media advocacy groups cheered the demise of the deal.Public Knowledge, an advocacy group that has been critical of the FCC under Pai, has been against a tie up between Sinclair and Tribune from the start.“While what has apparently killed this deal was Sinclair’s pattern of deception at the FCC — a fact that should affect its future dealings at the Commission — the deal was bad on its own merits, and this latest development is good for consumers,” said Phillip Berenbroick, senior policy counsel at the organization. “Broadcasters are supposed to serve their local communities. This deal would have contributed to the trend where ‘local’ news and ‘local’ programming is created or scripted out of town.”last_img read more

Patient falls off bed, dies; kin allege medical negligence

first_imgKolkata: A woman died after she fell off the bed at the newly built super-specialty hospital in Bongaon on Wednesday night.The family members of the patient have brought the charges of negligence against the hospital authorities and demanded a probe into the incident. Munmun Mondal (43), a resident of Chalki village at Gopalnagar in Bongoan was admitted to the hospital by her family members on April 23 as she complained of severe respiratory distress. Also Read – Bengal family worships Muslim girl as Goddess Durga in Kumari PujaAfter a preliminary check up the patient was admitted to the female medicine ward of the hospital. The patient was recovering well as observed by the hospital doctors. The family members of the victim spoke to the attending doctor in the night of April 24 who told them that patient may be released from the hospital in one or two days. The incident triggered tension among the patients at the female ward of the hospital on Thursday morning. The victim’s family members said that they received a phone call from the hospital saying the patient died. The family members then rushed to the hospital and came to know that the patient fell on the floor from the bed and this led to her death. It is suspected that she suffered internal injuries after falling from the bed. The real cause of her death is yet to be ascertained. The hospital staff members however denied the allegation of negligence. They termed it as an accident. The family members met the hospital authorities and urged them to conduct a probe into the death. They also alleged that the patient died due to negligence by a section of the hospital staff members. The hospital officials assured the deceased’s family members that a probe would be conducted into the incident.last_img read more

Ohio State mens wrestling readying itself for National Duals after loss to

The No. 5 Ohio State wrestling team is trying to bounce back after losing its regular season finale against No. 1 Penn State, 29-18, as it heads into the 2013 NWCA/Cliff Keen “Mat Mayhem” National Duals. The Buckeyes, which received an automatic bid to the event’s finals because they are among the top four returning dual-meet teams, finished the regular season 11-3 and 5-3 in the Big Ten. The automatic bid finalists were awarded based on their performance and rankings from the 2011-2012 season. OSU sophomore Hunter Stieber, ranked No. 2 in the 141-pound weight class, said that he likes the team’s chances in the postseason. “I feel pretty good,” he said. “Team-wise, I think we’ll be all right. We bounce back pretty well. We’re an older team so it should be good.” The Division I National Duals will feature a new format this year with eight teams in the finals instead of the traditional four. The addition of four automatic bid finalists increases the initial pool of competitors from 16 to 20. The teams that did not receive automatic bids are divided up into four different regions: Cornell University Region: Cornell, Hofstra, Virginia, Nebraska Kent State University Region: Kent State, Oklahoma State, Northern Iowa, Wisconsin Oregon State University Region: Oregon State, Oklahoma, Virginia Tech, Michigan University of Missouri Region: Missouri, Maryland, Wyoming, Purdue The automatic bid finalists are Ohio State, Iowa, Minnesota and Illinois. Each region will host a one-day competition Sunday. The winners will move on to join the four automatic bid teams at the University of Minnesota for the finals on Feb. 22-23 in Minneapolis. Sophomore 149-pounder Cam Tessari said he is looking to pick up where he left off coming off a big 3-1 win against then-No. 7-ranked sophomore Andrew Alton of Penn State. “I’m excited for it (the National Duals),” he said. “I was a little rocky at the beginning of the season but I think I’m starting to hit my stride.” OSU coach Tom Ryan said there are a few kinks the team needs to work out between now and the tournament, but he has high hopes. “I feel great about this team,” he said. “Up and down the lineup we have good guys. We have to fight a little harder, but we’re going to be ready to go.” Last year, OSU failed to make the finals of the National Duals when it lost to Oklahoma State in Stillwater, Okla. This year, they’ll look to avenge that loss. The Buckeyes’ first match is set to start at 6 p.m. on Feb. 22 at Williams Arena in Minneapolis, Minn. The finals will conclude Feb. 23. read more

Ohio State field hockey splits weekend slate

OSU freshman midfielder/forward Maddy Humphrey makes a play on the ball during a game against Ball State Sept. 14. at Buckeye Varsity Field. OSU won 3-2 in OTCredit: Melissa Prax / Lantern photographerTwo first-half goals from freshman midfielder Maddy Humphrey propelled Ohio State field hockey to a 3-1 victory against the Kent State Golden Flashes Sunday afternoon.Humphrey opened the scoring with a breakaway finish one-on-one with Kent State sophomore goalkeeper Andrea Rinehart just a little more than two minutes into the game at Buckeye Varsity Field.Three minutes later, she struck again, scoring on a rebound from junior back Emma Royce’s penalty corner shot.The early lead gave OSU (5-8, 0-4) the confidence to stay aggressive throughout the game against Kent State. Buckeye coach Anne Wilkinson said the team fed off the energy of Humphrey’s early goals.“They’re not playing like they’re behind the eight ball,” Wilkinson said of her team playing from ahead. “You just see (freshman forward) Annabel Sams and (freshman midfielder) Morgan Kile taking off with speed, and their speed kills.”OSU dominated in shots, 24-7, and penalty corners, 15-4, Sunday. It took Kent State (5-8) until the 17-minute mark of the second half for the Golden Flashes to pick up their first penalty corner opportunity.With momentum appearing to swing toward Kent State, Wilkinson called a timeout to regroup with 15:27 left in the game while nursing a 2-0 lead.Sams came out of the timeout and dribbled coast-to-coast to score an unassisted goal, giving OSU a 3-0 advantage.“I think we were one today,” Sams said. “And that showed. I think we had good connections and once we got the ball, we were really an attacking force.”Kent State got on the board with 11:52 remaining on a tip-in goal from senior forward Hannah Faulkner. The goal was Faulkner’s 10th of the season, but came too late in a game where OSU refused to give up possession.Humphrey’s two goals gave her 11 for the season as a part of her 30 points total, which both lead the team. Humphrey said she was pleased with the performance, but added the team needs to convert more on its penalty corner opportunities.“We unfortunately didn’t finish a lot of our corners today, which we’ll work on,” Humphrey said. “But just keep attacking and attacking (was) the mentality. They were getting frustrated and it kept pumping us up to shoot more.”The Buckeyes’ Sunday triumph came two days after they fell in a conference matchup.OSU couldn’t manage to get its first Big Ten victory Friday in Piscataway, N.J., against conference newcomer Rutgers.The Buckeyes and Scarlet Knights were tied at halftime, 1-1, when Rutgers (6-7, 1-4) went on a quick scoring spurt to put OSU away.Redshirt-sophomore midfielder Alyssa Bull took a cross in front of the cage from sophomore forward Rachel Yaney and finished to give Rutgers a 2-1 lead.Five minutes later, junior forward Katie Champion put the game out of reach, scoring on an assist from sophomore forward Jasmine Cole.OSU added a late goal from Royce, but ultimately fell, 3-2.Wilkinson said the team has to be more physical if they want to make a late run in the Big Ten Tournament in November.OSU is set to face Indiana on Friday in Bloomington, Ind., at 3 p.m. before taking on Iowa on Sunday at Buckeye Varsity Field at noon. read more

FIVE CAYS MEMBER getting street lights for Community

first_img Related Items:five cays, sean astwood, street lights Facebook Twitter Google+LinkedInPinterestWhatsAppProvidenciales, 7 Nov 2014 – FIVE CAYS MEMBER getting street lights for Community. Explaining that “at my request Fortis TCI has begun carrying out operations for the restoration and repairs to the Street lights in our community.”Hon Astwood says: ” If you are aware of any lights that are not operational please contact me asap via 231-4699 or seanastwood@gmail.com. Also if there are dark areas that you think street lights should be install, let me know as well so that I may make representation for additional lights in those areas. Budget cuts hurt, but necessary says TCI Deputy Premier in parliamentary debate on hurricane funds PDA takes rally to Five Cays Recommended for you Facebook Twitter Google+LinkedInPinterestWhatsApp Fire in Five Cays will leave many homelesslast_img read more

Supreme Court To Hear Appeal From Alaska Hovercraft Owner

first_imgSturgeon won an earlier round at the Supreme Court in 2016. The justices agreed Monday to review a federal appeals court ruling that sided with the National Park Service and against Sturgeon. Facebook0TwitterEmailPrintFriendly分享WASHINGTON (AP) — Alaska resident John Sturgeon is getting a second crack at the Supreme Court in his fight to get his hovercraft back on the Yukon-Charley Rivers National Preserve. The new case will be argued in the fall.center_img The dispute is over whether the federal government or Alaska has authority over the river inside the boundaries of the preserve. Sturgeon sued the Park Service in 2011 after it told him to stop operating his hovercraft on a stretch of the Nation river that passes through the federally created preserve.last_img

Cover Price Experiments

first_imgSome of us may remember back in 2007 when celebrity lifestyle magazine OK! made the decision to increase its cover price. Like a copycat younger sister, Bauer Publishing followed suit.But after more than two years of solid newsstand performance, Bauer’s Life & Style and In Touch took a tumble, dropping 30 percent and 27.7 percent in overall paid circulation and 30.2 percent and 28.7 percent in single copy sales, respectively, in the first half of 2008, according to ABC’s Fas-Fax survey. A Bauer spokesperson attributed this to “celebrity weeklies increasing their prices across the board, resulting in a 10 percent decline in newsstand sales for the first half of this year.”OK!, however, saw single copy sales increase 19.4 percent and verified circulation up 11.8 percent during the first half of 2008, after upping its cover price to $2.99 in 2007. Being “in sync with what readers are looking for” is key to the magazine’s success, says OK! general manager Kent Brownridge. “It’s all a perceived value question.” When OK!’s price increased again to $3.49 in mid-2008, the magazine experienced no decline in newsstand sales.Are increased cover prices really the culprit in Bauer’s newsstand slide? Brownridge offers that Bauer’s cover prices were “amazingly, dramatically low,” and that in his opinion, they are now at the proper cover price of $2.99; high former sales were a result of “ridiculously low [cover] price[s].” While this may be old news, “sales on newsstands have been dropping for reasons other than just cover price,” says Active Interest Media COO and group publisher Andrew Clurman. Here, publishers discuss what factors, other than cover prices, allow titles to stay ahead.‘Newsstand Darwinism’TAM Communications owner Buzz Kanter cites “Newsstand Darwinism” as the main component of sales: only the strong and swift to react to the market will survive. In his own overcrowded field of automotive and motorcycle magazines, Kanter expects as much as one third of the titles to fold in the coming year. Wholesalers and retailers, he thinks, will promote category leaders, while weeding out those titles that can’t keep up.In 2008, Active Interest Media raised cover prices on Backpacker and Blackbelt from $3.99 to $4.99 and $4.99 to $5.99, respectively. “Cover price increases contribute to the fall, but value also plays a great part in sales. As the economy becomes tighter, people are more selective in what they’re buying,” says Clurman. He determines cover price by looking at the category, competitive titles and where the market is. Clurman also considers which way sales are trending. “If you think you’re below the competition, increase the cover price,” he says.Kanter’s Harley-Davidson focused magazine, American Iron, has experimented with bumping cover prices, resulting in no sales fall off, as well as lowering it to offer better value to readers, and decent profits to wholesalers and retailer partners. American Iron has remained at its cover price of $5.99 since early 2008. The cover price for RoadBike, Kanter’s smaller circulation magazine focusing on import bikes, is “much less aggressive,” only raising its cover price a total of $2—from $2.99 to $4.99—over the past decade. In Clurman’s experience, lower prices have never lifted sales. “We haven’t gone down to $.99, but we’re selling niche publications to a self-selecting audience. They’re not a market heavily influenced by a $.99 or $1 difference.”  2009 DecisionKanter jokes that it doesn’t take six PhDs and a Ouija board to make a decision on newsstand price. “We’ve found that American Iron’s single copy sales are relatively flat, but virtually all of the competing titles are significantly down,” he says. In 2009, Kanter has decided to let cover prices ride. Clurman cites Backpacker and Blackbelt’s sales as flat in 2008, and has also made the decision not to increase cover prices in 2009. Brownridge’s intention for OK!? “We won’t raise it in near future. It’s right where it should be.”last_img read more

Publishers Respond as Online Consumer Data Privacy Concerns Arise

first_imgMany of the tech-savvy subscribers to Technology Review online know all about behavioral tracking cookies and either delete them manually or hit TR’s privacy page and opt out. There are also those that ignore them. None of these actions surprise TR, which designed its privacy policy to give readers better control over who sees their surfing habits and why. “We are very clear in our privacy policy. We will cookie; we track behavior; we allow them to do one-click opt-outs,” says Heather Perry Holmes, senior vice president of audience development at TR. “A lot of what drives us is that we put ourselves in the customer’s shoes.”That philosophy is in line with the Federal Trade Commission’s recent proposal to improve consumer online data protection with a universal do-not-track mechanism for data collection and tracking by third parties. FTC states that some Internet users are against the collection and sharing of their information, while some have no idea that it is taking place and others, who are aware, see it as a trade-off for desirable products or services.The agency says it has provided a framework for policymakers, including Congress, which has been grappling with the issue. This month [February] alone at least three bills have been introduced in the House involving increased consumer data privacy protection including opt-in or opt-out provisions. The increased attention is spurring the business community at large to step up self-regulation efforts, analysts say. Google, Microsoft, and Mozilla have each recently announced tracking protection for their respective Web browsers. But critics argue that the new browser options are only as good as the Web sites that choose to honor them. They say the number of bad actors on the Web has not diminished, which makes even the good actors look bad.Dennis Dayman, chief privacy officer at Eloqua, which focuses on collecting and analyzing data for businesses, embraces what he calls “hypertransparency” for anyone conducting business on the Web. He says it is in every business’s best interest to provide end users with notice, consent and choice.End users should be “told in plain English and in non-legal terms what’s going to happen to their data and how you are going to use it,” Dayman says. They should know that by filling out a form, for example, they will receive an e-mail.Sal Tripi, senior director of operations and compliance at Publishers Clearing House, says consumer data privacy protection should be a concern for anyone that does business online. However, “the bigger issue is that the government feels the need to add regulation because consumers have concerns,” he says.Given the enormous amount of content on the Web that is funded by advertisers, “the absence of effective advertising will, no doubt, limit what’s available on the Internet,” he says. “But I don’t think it’s an all-or-nothing scenario,” providing that the business community comes together to raise data protection “to a level that consumers feel comfortable with,” he says.PCH teamed up with online privacy services firm TRUSTe last year to launch a behavioral advertising notice-and-choice pilot program on the PCHlotto.com site. Ads on the site included an “interest-based ads” icon that, when clicked, engaged a widget providing information about ads and ad networks. It also allowed users to control preferences or opt-out of online behavioral advertising (OBA).The program, which is now being rolled out to all PCH sites, was “a smash hit” and showed that consumers have a high comfort level for OBA when they are well-informed about how it works, Tripi says. “Not many” end users opted out of the ads, he says, “and a fair amount engaged with the widget.”Parade magazine chose a different route, partnering with video advertising network AdGenesis to launch the Parade Video Rewards program in January. The program asks users to provide detailed information about interests and purchase intentions. In turn, they receive personalized and targeted branded video content and commercials.Meanwhile, TR reviews and tweaks its privacy policy annually to make sure it is on target with business and consumer concerns, Holmes says. “We believe that our users flush the cookies frequently,” she says. “But that’s just the product of having a tech audience,” which has not stopped returning to the site.last_img read more

LIVE MUSIC in Wilmington Week of October 7 2018

first_imgWILMINGTON, MA — Here are several opportunities to catch live music in Wilmington this week:Counterfeit CashFriday, October 12, 7pmWilmington Middle School25 Carter Lane, WilmingtonKaraoke with Winnell EntertainmentFriday, October 12, 8pmPacific Grove211 Lowell Street, WilmingtonTom ColantuoniSunday, October 14, 10am-1pmWilmington Farmers MarketSwain GreenNOTE: Know of any other musical performances happening in town this week or in the coming weeks?  Let me know at wilmingtonapple@gmail.com.Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedLIVE MUSIC in Wilmington (Week of July 8, 2018)In “Business”LIVE MUSIC in Wilmington (Week of September 23, 2018)In “Community”What To Expect At The Wilmington Farmers Market On August 11In “Community”last_img read more

ICICI Prudential Life Insurance continues to disappoint investors

first_imgThe initial public offering (IPO) of ICICI Prudential Life Insurance has proved to be a dampener for millions of investors who subscribed to the IPO hoping to get a good return quickly after the listing. The issue was oversubscribed 10 times and the shares were issued at Rs. 334 per equity share. After being listed on the bourses at a discount on September 29, ICICI Prudential Life stock continues to trade below the issue price.ICICI Prudential Life Insurance stock listed at Rs. 329 on Thursday and lost further to close at Rs. 297.65. The historic high for the scrip is Rs. 333.90, a tad short of its listing price (Rs. 334). On Monday, October 3, the stock was trading at Rs. 309.90 on the Bombay Stock Exchange (BSE) at around 2.10pm, down 0.06 percent to its Friday close of Rs. 310.10.ICICI Bank shares were up 1.19 percent at Rs. 255.30 apiece on the BSE. The ICICI Prudential Life Insurance public issue was basically its parent ICICI Bank offloading 181.3 million shares via offer-for-sale route.It may be recalled that brokerages were mixed in their assessment of 16-year-old ICICI Prudential Life Insurance’s valuation. Some were of the view that the offer was worth investing, while others were guarded.”Considering healthy business momentum, rising penetration for insurance sector as well reasonable valuations for the company, we recommend SUBSCRIBE to the issue,” Mumbai-based Quant Broking Private Limited said in its IPO note. However, another brokerage had a contrarian view.”At the price of band of ‘300-334 the issue is offered at 3.1x and 3.4x its reported FY16 EV. While the company has enough scope for business growth in the future, we believe the issue is fully priced in and hence we have a NEUTRAL rating on the issue,” Angel Broking had said in its note on September 16, three days prior to the opening of the Rs. 6,057-crore public issue.ICICI Prudential Life Insurance was incorporated as a joint venture between ICICI Bank and UK’s Prudential Corporation Holdings. As of June 2016, Company has 1,24,155 individual agents and their bank partners had over 4,500 branches, Sushil Finance Consultants said in its note. ICICI Prudential Life Insurance reported net profit of Rs. 1,653 crore on net premium income of Rs. 18,999 crore in 2015-16.On Monday, the BSE Sensex was trading at 28223.30 at 2:36pm, up 357.30 points from it previous close.last_img read more

Cardinals Travel to Virginia Tech For a Second Straight Top 25 Matchup

first_img Jordan Nwora is the second-most improved scorer in the nation with his 17.9 scoring average (fifth in the ACC) up 12.2 ppg from his 5.7 average last year. He has scored 20 or more points on 10 occasions this season. Dwayne Sutton has had double-doubles in four of the last eight games. He led the Cardinals with a career-high 19 points, eight rebounds, two blocked shots and two steals against North Carolina. He has scored in double digits in 10 of the last 13 games. Louisville’s 7-2 record in ACC games matches its best nine-game start in its five years in the ACC, tying the Cardinals’ 8-2 start in 2015-16. Christen Cunningham had 15 points and nine assists against North Carolina, his second highest assist total of the year. He leads the ACC in assists in conference only games (6.6). He has handed out 43 assists with just nine turnovers in his last six games. Louisville has allowed less than 55 points in three of its last five games. The Cardinals have limited an opponent to under 40 percent accuracy for a half on 19 occasions this season, including holding North Carolina to 35.3 percent in the second half of its last game. Louisville is 27th in the nation in adjusted defensive efficiency by Kenpom. UofL has scored 80 or more points in 13 of its 22 games (79.1 ppg) and the Cardinals are 16th in the nation in adjusted offensive efficiency by Kenpom. UofL is third in the ACC in scoring offense for conference games (81.1 ppg). Louisville’s 2019 signing class is ranked second in the nation by ESPN.com, fifth by Rivals.com and fifth by 247sports.com.Print Friendly Version Virginia Tech Notes GAME 23Date: Feb. 4, 2019Time: 7:00 p.m.Site: Cassell Coliseum, Blacksburg, Va. (9,100)Television: ESPN Big Monday – Sean McDonough, play-by-play; Jay Bilas, analyst;Allison Williams, reporter.Radio: WKRD (790 AM; joined in progress on WHAS, 840 AM) Paul Rogers, play-by-play; Bob Valvano, analyst (XM channel 380, Internet 971)Series History: Louisville leads 33-8 (17-3 in Louisville, 15-3 in Blacksburg, 1-2 neutral)Last Meeting: UofL 75, Virginia Tech 68 (Feb. 24, 2018 in Blacksburg, Va.)UL National Ranking: 15th Associated Press, 16th USA Today (Jan. 28 poll)Officials: Mike Stephens, Jeff Clark, Doug SirmonsNext UofL Game: Feb. 9 at Florida State, Tallahassee, Fla., 4 p.m. ET (ESPN/2/U) The Hokies are second in the nation in three-point field goal percentage (.422), seventh in field goal percentage (.497), sixth in scoring defense (60.2) and 18th in assist/turnover ratio (1.42). Four Hokie players are averaging over 12 points a game, led by sophomore guard Nickeil Alexander-Walker (17.6 ppg). Four Hokies have made at least 37 three-pointers this season. Virginia Tech is No. 9 in the Sagarin Ratings, No. 6 in ESPN’s College Basketball Power Index (BPI), No. 9 in the NET rankings and No. 8 by Ken Pomeroy through Feb. 2. Louisville fell for the first time in seven games as the Cardinals lost 79-69 to No. 9/10 North Carolina on Saturday when UofL was beaten 49-32 on the boards. Dwayne Sutton scored a career-high 19 points and grabbed eight rebounds for the Cardinals while Christen Cunningham totaled 15 points and nine assists. The Cardinals are very balanced on the offensive end, with five players averaging over eight points.  Sophomore Jordan Nwora leads the Cardinals in in scoring and rebounding with 17.9 points and 7.7 rebounds per game.   Dwayne Sutton ranks second on the team in scoring with 10.6 points along with 6.9 rebounds per game. Christen Cunningham is third on the team in scoring with 10.4 points and leads the team with 96 assists on the year.  Steven Enoch averages 9.3 points per game along with 5.3 rebounds per game while Malik Williams is averaging 8.1 points and pulling down 5.3 rebounds per game. Virginia Tech has won four of its last five games, including a stunning 47-24 victory at NC State in its last game on Feb. 2 in which it held the Wolfpack to 16.7 percent shooting for the game (9-of-54), including 2-of-28 shooting from three-point range (.071). CARD FILES Live Stats Louisville leads 33-8 in its series against Virginia Tech, winning the last 14 matchups and 25 of the last 27. UofL prevailed in both meetings last season: 94-86 in the KFC Yum! Center (1-13-18) as Deng Adel scored a career-high 27 points and grabbed 11 rebounds to lead the Cardinals; and 75-68 in Blacksburg, Va. (2-24-18) as Quentin Snider scored 22 points and handed out six assists.  Louisville, ranked 15th by AP and 16th in the USA Today poll (Jan. 28), plays its second of four straight Top 25 foes as the Cardinals play the first of two consecutive games on the road at No. 12/11 Virginia Tech in Blacksburg, Va. on Monday. Louisville Game Notes Story Linkslast_img read more

Recap Accident involving three lorries on the M6 caused miles of tailbacks

first_imgDad slams ‘disgusting’ hospital window Punter found hiding in bushes There were long delays on the M6 motorway in Cheshire this morning due to an accident involving a number of lorries . Inrix, the traffic data company reported severe delays and queueing traffic for nine miles due to accident on the Northbound carriageway. Three lorries were involved in the collision on the M6 Northbound carriageway from J18 A54 Middlewich Road (Middlewich /  Holmes  Chapel) to J19 A556 ( Knutsford ). In the roadworks area. Lanes two and three (of three) were blocked half a mile before J19, with the carriageway closing fully shortly before 8am – although all lanes reopened at around 10am. Inrix first reported the accident shortly before 7.20am today (January 16 2019). A Highways England spokesman said:  “All lanes have re-opened on the M6 northbound between J18 and J19 following a collision. Severe delays of approx 70 minutes above normal travel time , this should start to ease now all lanes are clear. “Road users intending on using this section of road are advised to allow plenty of extra time for their journey and to consider alternative routes (if possible).” Cheshire Fire and Rescue Service confirmed they had attended the scene. A fire service spokeswoman said:  “At around 7.30am firefighters were called to reports of a collision on the M6 northbound, between junctions 18 and 19. On arrival crews discovered that the collision involved three heavy goods vehicles. “Lanes two and three were closed as emergency services dealt with the incident. No-one was trapped in any of the HGVs. Firefighters made the vehicles safe and were in attendance for nearly half-an-hour. “The Highways Agency, police and paramedics also attended. Firefighters liaised with the police about safety and the recovery of the vehicles.” Read MoreTop stories on StokeonTrentLive Driver named following fatal collisioncenter_img Police search for missing woman   Traffic England also confirm delays of around 90 minutes – with congestion now reported back past junction 18. North West Motorway Police have also reported congestion is building. Read MoreThese two city centre roads are shut for the next SIXTEEN weeks (and here’s why)   A spokesman said:  “We currently have a collision on M6 northbound just near to Knutsford services. Police and Highways England at scene. A lot of congestion being caused by the collision. We are working to clear it as soon as possible.”10:47Statement from the fire serviceA Cheshire Fire and Rescue Service spokeswoman said; At around 7.30am firefighters were called to reports of a collision on the M6 northbound, between junctions 18 and 19.On arrival crews discovered that the collision involved three heavy goods vehicles.Lanes two and three were closed as emergency services dealt with the incident.No-one was trapped in any of the HGVs.Firefighters made the vehicles safe and were in attendance for nearly half-an-hour.The Highways Agency, police and paramedics also attended.Firefighters liaised with the police about safety and the recovery of the vehicles.” 10:45Photos from the scene earlier (Image: North West Motorway Police)10:07Highways England confirm all lanes have reopenedA Highways England spokesman said:All lanes have re-opened on the M6 northbound between J18 and J19 following a collision. Severe delays of approx 70 minutes above normal travel time , this should start to ease now all lanes are clear. “10:00Inrix reporting lanes reopenedInrix, the traffic data company are now reporting ten mile queues but all lanes reopened.09:44Latest from Highways EnglandA Highways England spokesman said:2 Lanes remain closed on the M6 northbound between J18 and J19. Delays of over 2 hours from J17. Please take into account if you’re heading to Manchester Airport.”09:28Traffic England reporting delays of two hours againTraffic England are again reporting delays of two hours against expected traffic.09:22Lanes remain closedTwo lanes closed, severe delays and queueing traffic for ten miles due to recovery work and accident, multiple lorries involved on M6 Northbound from J18 A54 Middlewich Road (Middlewich / Holmes Chapel) to J19 A556 (Knutsford). Congestion to J17 (Sandbach / Crewe). In the roadworks area. Travel time is around 1 hour and 50 minutes.Lanes two and three (of three) still remain closed. Traffic was held between 08:45 and 08:50 while recovery was ongoing.09:07Only two lanes closed againOnly two lanes closed again08:49Traffic being held againWe’re now getting reports traffic is again being held on the M6 08:43Delays of one hour and 45 minutesInrix are now reporting delays of one hour and 45 minutes.08:31Queueing traffic on exit sliproadQueueing traffic on exit slip road due to traffic exiting early on M6 Northbound at J17 A534 Old Mill Road (Sandbach / Crewe). In the roadworks area.Traffic is avoiding the accident further up the motorway between J18 and J19. 08:29Impact on surrounding roadsDelays on the M6 are having an impact on surrounding roads.Queueing traffic due to the problems on the M6 on A534 Southbound from M6 J17 (Sandbach / Crewe) to A533 Old Mill Road.Queueing traffic due to the problems on the M6 on A54 Middlewich Road Eastbound from M6 J18 (Middlewich / Holmes Chapel, Sproston) to B5308 (Holmes Chapel).Queueing traffic due to the problems on the M6 on A50 London Road Westbound from A5022 Holmes Chapel Road (Brereton) to A54 Chester Road (Holmes Chapel). 08:22One lane has now reopened – but 90 minute delays continueA Highways England spokesman said:1 Lane has re-opened on the M6 northbound between J18 and J19. Delays are currently around an hour and half above normal journey times .”08:18Nine mile queues now reportedNine mile queues are now reported on the motorway.08:16Queuing traffic southbound due to people looking at accidentQueueing traffic due to people slowing to look at accident on the opposite side on M6 Southbound from J19 A556 (Knutsford) to J18 A54 Middlewich Road (Middlewich / Holmes Chapel). In the roadworks area.08:12Motorists advised to find alternative routesA Highways England spokesman said:Road users intending on using this section of road are advised to allow plenty of extra time for their journey and to consider alternative routes (if possible).” 08:09Delays of two hours now reportedInrix are now reporting delays of up to two hours08:05Northbound now completely blockedThe M6 Northbound is now completely blocked. Highways England have confirmed.A spokesman said:The M6 northbound between J18 and J19 is now blocked. Delays are currently about an hour and a half above normal journey times. Please allow extra time if you’re heading to Manchester Airport.”08:01What we know so farTwo lanes are closed and long delays are reported on the northbound M6Three lorries are involved in the accident, which has taken place just before junction 19Delays of up to 90 minutes are currently being reported.07:56Accident near Jodrell Bank adding to delays in CheshireA Cheshire Police spokesman said:A535 HOLMES CHAPELTO CHELFORD – 2 vehicle collision by Jodrell Bank – 1 lane closed – large build up of traffic already, so please avoid the area and find alternative routes .”07:49Police at the sceneNorth West Motorway Police are the scene of the collision.A spokesman said:We currently have a collision on M6 northbound just near to Knutsford services. Police and Highways England at scene. A lot of congestion being caused by the collision. We are working to clear it as soon as possible.” 07:48Affected stretch of carriagewayThe accident has taken place between Junction 18 and Junction 19 (Image: Inrix)last_img read more

Mexico Tourism Boards Mendoza officially signs off from 2 Bloor St West

first_img Travelweek Group Friday, March 1, 2019 << Previous PostNext Post >> Posted by TORONTO — Cesar Mendoza, Regional Director, Canada for the Mexico Tourism Board, is saying farewell for now – but hopefully not goodbye – as the Toronto office of the Mexico Tourism Board closes its doors today, March 1.The Mexico Tourism Board has been active in Canada for decades. The Toronto office, located at 2 Bloor St. West, will be closed indefinitely, confirms Mendoza.As reported on Travelweek.ca, and in the Jan. 24, 2019 issue of Travelweek, MTB offices around the world are closing at part of a restructuring plan brought down by Mexico’s new government.“Mexico’s new elected federal government recently decided that every international promotional effort – both economic and tourism related – will be handled by our Embassies and Consulates around the world,” says Mendoza.“It has been an absolute honour working and getting to know so many great professionals like yourself for more than 15 years. I will always remain an avid and proud promoter of my beautiful country.”center_img Share Mexico Tourism Board’s Mendoza officially signs off from 2 Bloor St. West Tags: Mexico Tourism Boardlast_img read more

That title wouldnt make for much of a campaign sl

first_imgThat title wouldn’t make for much of a campaign slogan, and yet, it’s the natural outcome of one particular politician’s promise. Most of the notes I receive about the Affordable Health Care Act, or Obamacare, are first-person accounts of how a reader’s change in coverage or cost is affecting his life. These stories prompted several discussions with Andy Mangione, vice president of government relations of the Association of Mature American Citizens (AMAC). Andy serves as the lead legislative and government contact for AMAC in Washington, DC. He’s also responsible for national grassroots outreach and developing strategic partnerships. Andy is AMAC’s man on the scene in Washington, and he kindly agreed to sit down for an interview on the significant budget cuts to home health care that have been made as a result of Obamacare. I’ll let Andy get into the details.Dennis Miller: Welcome, Andy. Thanks for taking the time to educate our readers on the latest goings-on in Washington.Andy Mangione: My pleasure, Dennis.Dennis: Andy, let’s get right to it. I know you’re very concerned about how cuts to home health care will impact seniors. This is no longer a theoretical problem. I’d like to ask a two-part question: Can you tell our readers a bit about your organization and how these budget cuts will affect “mature American citizens?”Andy: Dan Weber, a private citizen, founded AMAC as an alternative to and competitor of AARP. AMAC is a right-of-center, conservative member benefits and senior advocacy organization for Americans age 50 and older. AMAC offers many of the same benefits and services as AARP. The biggest difference, though, is our approach to advocacy. AMAC is a member-driven organization. We do not sit in a boardroom and determine our stance on issues unilaterally. We take our marching orders from our members. They determine the issues that I bring to Washington, DC and help us to determine our policy and issues positions. We have over 1.2 million American members living in all 50 states. We add approximately 1,000-2,000 new, dues-paying members each week. I think it’s important to describe the Medicare home healthcare recipient before getting into the cuts. The average age of this beneficiary is 82. Two-thirds live below the federal poverty level, and they have chronic illnesses like heart disease, COPD, and diabetes. These are Medicare’s oldest, sickest, and poorest beneficiaries. Most of these folks reside in rural areas, and the majority of them are women. The $22 billion cuts over four years to Medicare home health care will mean these homebound seniors will have to seek care outside of their homes. The cuts will also devastate the home healthcare sector. And where will the money from these cuts go? To fund subsidies on the insurance exchanges and to expand Medicaid—two key components of Obamacare.Dennis: I recently wrote an article about long-term care insurance, which many refer to as nursing home insurance. I pointed out that a major provision of long-term care is home health care, which is actually “avoid nursing home insurance.” If the government is cutting back on money for home health care, what options will be available for those who need care?Andy: They’ll be forced to receive care in nursing homes or other institutional settings, which greatly increases their cost and negatively affects their healthcare outcomes. Also, keep in mind that most recipients of Medicare home health care reside in rural areas and do not have the same choices for nursing home or other institutional care that those who live in urban areas do.Dennis: Won’t that further overload hospitals and nursing homes, which in turn will add to the overall costs?Andy: Absolutely. Medicare home health care saved the Medicare program $3 billion over the last three years. Expenditures for non-Medicare home health care will definitely rise since these patients will be treated in nursing homes and other institutions.Dennis: I don’t know of anyone who, given a choice, wouldn’t prefer to stay at home for care. What impact will these budget cuts have on the home healthcare industry?Andy: The Centers of Medicare and Medicaid Services (CMS) looked at these cuts and estimated that nearly 500,000 jobs in the home healthcare sector will be lost. They also estimate that 5,000 home healthcare companies will become insolvent as a result of these cuts by 2017.Dennis: You touched on something I hadn’t thought through before: the significant impact these cuts will have on working women and small-business owners. What can people do now? The budget cuts have already been passed. Is it too late?Andy: It’s not too late. H.R.5110, the SAVE Medicare Home Health Act, was recently introduced to rescind these cuts and replace them with commonsense accountability for home healthcare agencies, which would increase the quality of care for patients. The House will vote on the budget-neutral H.R.5110 in the fall, and if it passes—and it has a good chance of doing so—then it’s on to the Senate. If you would like to reach out to your Congressional representatives to urge them to support H.R.5110, please feel free to visit our home healthcare site. 90% of the businesses that provide home health care are small businesses. And, as I previously mentioned, CMS estimates that 5,000 of these businesses are at risk of closing their doors as a result of these cuts. Women own the majority of these businesses, and the majority of their employees—the nurses and other allied health professionals who provide care—are also women. CMS also estimated that 500,000 of these jobs are threatened by these cuts. That’s a lot of women-owned businesses and female employees drastically affected by these cuts. Also, the vast majority of the patients receiving home health care are women. Any way you evaluate it, these cuts to home health care disproportionately affect women in a very negative way.Dennis: I’d like to ask one question on a different topic. When I’ve written about Obamacare in the past, I’ve received three forms of feedback. The first was genuine concern, and the second was political criticism. Third, I heard from a large group that basically has a hard time believing it. Their sentiment was: “That just could not happen in America!” How do you respond to people who are having a hard time believing that Obamacare is going to have a major and possibly negative impact on their lives and their health care?Andy: I would say that elections have consequences. Not only can this happen in America, it already has happened! President Obama burst onto the national scene promising hope and change and certainly delivered on the “change” promise. Only it was not the change that most Americans were seeking. Like it or not—and AMAC members most definitely do not like it—Obamacare is now the law of the land. All is not lost, though. There’s always another federal election every two years, when Americans have the opportunity to right the ship and elect people who identify with their values and beliefs. Get involved and research candidates before giving your precious vote to an articulate, attractive candidate who looks great in a suit. Take the time to find the substance behind the style.Dennis: Andy, on behalf of all our readers, thanks for sharing your boots-on-the-ground input. Hopefully our subscribers will pitch in and let their elected representatives know how they feel. I should share that I’m a card-carrying member of AMAC. While there are several organizations that claim to represent seniors, I’ve found that most don’t represent my views well. AMAC doesn’t donate to political action committees, individual campaigns, or endorse candidates. It does listen to its members and work on issues of major concern. Like many laws, the details of Obamacare have emerged after the law was passed. If those details frighten you, make sure the organizations you belong to reflect that sentiment.On the Lighter Side When you read this, Jo and I will be in San Antonio at the Casey Summit. We’re both looking forward to visiting the Alamo and enjoying the San Antonio River Walk. If you’re attending, please flag me down and say hello. If not, you can listen to all of the compelling presentations on the Summit Audio Collection. I recommend preordering to take advantage of the sizable discount. And finally… Until next week…last_img read more

Most Important Broadcast Of 250 Million Traders

first_imgMost Important Broadcast Of $250 Million Trader’s 3-Decade Career This reclusive millionaire was the moneymaking expert Fortune 500 Executives from Boeing and Chevron turned to. But now, he’s doing something unlike anything done before… you may be shocked and blindsided. Think before you click here. — Details on the “next Bitcoin” – Buy this top crypto pick now This crypto has a market cap well under $100 million… but it recently flashed the same buy signal as two other cryptos that soared 208% in three months… and 1,522% in eight months. For the next few days only, you can get all the details here. Justin’s note: Today, I’m featuring a new essay from one of the best value investors in our business, Bonner Private Portfolio editor Chris Mayer.Longtime readers know it pays to listen to Chris’ advice. Over a 10-year span, he outperformed not only the S&P 500, but also legendary investors like Warren Buffett and Carl Icahn. Chris was able to do this by finding hidden pools of value in the market. Below, he shares a little-known secret to uncover these gems… By Chris Mayer, editor, Bonner Private Portfolio Hard as it is to believe, there’s a large group of “investors” out there who don’t care about the price of what they’re buying. They don’t care about earnings, dividends, or any of that. They buy, no matter what. And the result is a market full of over-loved and overvalued stocks. We deal in strange markets these days, with bizarre, distorted prices. Seriously, I’ll prove it. Take a look at Coca-Cola’s annual revenue and share price from 2012–17: In 2017, Coca-Cola delivered another year of declining sales. And the stock was up again. So nothing has changed. A company can’t keep reporting lower and lower profits and somehow see the stock price continue to go higher and higher. Eventually, you get absurd prices. Today, I’ll show you the group of investors who are causing these distorted prices… and a little-known trick to fade—or counter—this trend to find value in the market. The Rise of Index Investors Companies like Coca-Cola can see their share prices rise, despite falling earnings, because of a practice called indexing. An example of indexing is when you put your money in an S&P 500 Index fund, or exchange-traded fund (ETF). These funds aim to mimic the returns of the S&P 500 by buying all the shares in the index in the exact proportion they are held in the index. The fees are very low. And since most actively managed funds can’t beat the index, index funds have become a popular option. Popular may be an understatement. The Vanguard Group—one of the largest providers of index funds and ETFs—has $4.5 trillion under management. That’s no typo. Trillion, with a “T.” The top 10 index firms report $9.2 trillion in indexed assets. That’s about a third of the value of tradable shares in the S&P 500. And the inflow continues. And those inflows are creating distortions. You have a steady buyer sending a tsunami of money into index funds as well as a limited number of big stocks. Indexers don’t care if Coca-Cola is overvalued. If it is in the index, the index fund has to buy it. Period. Over the years, this creates odd effects on the pricing of those stocks in the index. Few do a better job of documenting these distortions than Murray Stahl, the chief investment officer and co-founder of Horizon Kinetics, a New York-based investment firm. Murray calls companies like Coca-Cola “revenue decliners.” In March 2017, Stahl warned that Coca-Cola was overvalued. He showed that sales and earnings had fallen since 2012. And yet the stock carried a premium valuation. “No one seems concerned that a highly caloric soft drink like Coca-Cola is losing market share to healthier alternatives,” he wrote. How to explain it? Coca-Cola is an index favorite. And the flood of money pouring into index funds gives stocks like Coca-Cola lots and lots of automatic buyers. I think it is a leading contributor to overvaluation. Where to Find Value Today Here’s a little-known secret of how S&P constructs its index: The focus is on the market cap, as indicated by the float. The float is the number of shares outstanding less shares held by insiders. Thus, the index overweights shares with low insider ownership, like Western Union. And it underweights shares with high insider ownership, such as Berkshire Hathaway. That’s the exact opposite of what a smart investor would do. Instead of piling into overvalued index funds, you should be attentive to the differences between companies. It may not feel like it because the indexers have done very well blindly betting on the S&P 500. But they are taking risks that will catch up with them eventually. In Bonner Private Portfolio, we continue to own firms that are either not in the S&P 500 or that are underweighted because of high insider ownership. That’s where we’re finding value. On the flip side, there is a steady supply of sellers of stocks not favored by indexes, as money flows away from the active managers who would typically hold such stocks and toward the indexers. The result is that you can find value in stocks not favored by the indexers. Now is a great time to be a stock picker. Regards,center_img — Recommended Link Recommended Link Chris Mayer Editor, Bonner Private Portfolio P.S. How should you approach your investments? How should you think about them? Those are the types of questions I tackle in my newest book, How Do You Know: A Guide to Clear Thinking About Wall Street, Investing & Life. How Do You Know? is full of ideas about investing—including one that hasn’t been part of the public investing discussion in nearly 60 years. But it’s not just another book on investing. My goal is not just to give you ideas, but to provide practical guidelines for uncluttering your thinking—that is, for getting unhelpful ideas and misleading information out of the way. You can order your copy of How Do You Know? in paperback or Kindle format right here… Reader Mailbag Today, a reader responds to our featured interviews (here and here) with cryptocurrency expert Teeka Tiwari on why the stage is set for another crypto rally… My main problem in purchasing cryptocurrencies is they are completely unregulated. Example. You buy tokens at a cryptocurrency IPO crowd sale. Then you try to make an inquiry into the cryptocurrency that you purchased. They don’t have to respond. They don’t have to provide you with ANY information that you may be requesting or inquiring about. They can drop the value of your cryptocurrency to worthless on the drop of a dime and owe no explanation, period. Please do not get me wrong. I like the idea of blockchain transactions. However, cryptocurrencies have a long road to travel before they become feasible as an exchange. For now, no thank you.—Albert Do you think now is a good buying opportunity in cryptos? Or are you staying on the sidelines? Let us know here. If you’d like to learn more about cryptos, we urge you to check out this new presentation from Teeka.last_img read more

Doctors at the National Institutes of Health say t

first_imgDoctors at the National Institutes of Health say they’ve apparently completely eradicated cancer from a patient who had untreatable, advanced breast cancer.The case is raising hopes about a new way to harness the immune system to fight some of the most common cancers. The methods and the patient’s experience are described Monday in a paper published in the journal Nature Medicine.”We’re looking for a treatment — an immunotherapy — that can be broadly used in patients with common cancers,” says Dr. Steven Rosenberg, an oncologist and immunologist at the National Cancer Institute, who has been developing the approach.Rosenberg’s team painstakingly analyzes the DNA in a sample of each patient’s cancer for mutations specific to their malignancies. Next, scientists sift through tumor tissue for immune system cells known as T cells that appear programmed to home in on those mutations.But Rosenberg and others caution that the approach doesn’t work for everyone. In fact, it failed for two other breast cancer patients. Many more patients will have to be treated — and followed for much longer — to fully evaluate the treatment’s effectiveness, the scientists say.Still, the treatment has helped seven of 45 patients with a variety of cancers, Rosenberg says. That’s a response rate of about 15 percent, and included patients with advanced cases of colon cancer, liver cancer and cervical cancer.”Is it ready for prime time today? No,” Rosenberg says.”Can we do it in most patients today? No.”But the treatment continues to be improved. “I think it’s the most promising treatment now being explored for solving the problem of the treatment of metastatic, common cancers,” he says.The breast cancer patient helped by the treatment says it transformed her life.”It’s amazing,” says Judy Perkins, 52, a retired engineer who lives in Port St. Lucie, Fla.When Perkins was first diagnosed and treated for breast cancer in 2003, she thought she’d beaten the disease. “I thought I was done with it,” she says.But about a decade later, she felt a new lump. Doctors discovered the cancer had already spread throughout her chest. Her prognosis was grim. “I became a metastatic cancer patient,” says Perkins. “That was hard.”Perkins went through round after round of chemotherapy. She tried every experimental treatment she could find. But the cancer kept spreading. Some of her tumors grew to the size of tennis balls.”I had sort of essentially run out of arrows in my quiver,” she says. “While I would say I had some hope, I was also kind of like ready to quit, too.”Then she heard about the experimental treatment at the NIH. It was designed to fight some of the most common cancers, including breast cancer.”The excitement here is that we’re attacking the very mutations that are unique to that cancer — in that patient’s cancer and not in anybody else’s cancer. So it’s about as personalized a treatment as you can imagine,” Rosenberg says.His team identified and then grew billions of T cells for Perkins in the lab and then infused them back into her body. They also gave her two drugs to help the cells do their job.The treatment was grueling. Perkins says the hardest part was the side effects of a drug known as interleukin, which she received to help boost the effectiveness of the immune system cells. Interleukin causes severe flu-like symptoms, such as a high fever, intense malaise and uncontrollable shivering.But the treatment apparently worked, Rosenberg reports. Perkins’ tumors soon disappeared. And, more than two years later, she remains cancer-free.”All of her detectable disease has disappeared. It’s remarkable,” Rosenberg says.Perkins is thrilled.”I’m one of the lucky ones,” Perkins says. “We got the right T cells in the right place at the right time. And they went in and ate up all my cancer. And I’m cured. It’s freaking unreal.”In an article accompanying the new paper, Laszlo Radvanyi, president and scientific director of the Ontario Institute for Cancer Research, calls the results “remarkable.”The approach and other recent advances suggest scientists may be “at the cusp of a major revolution in finally realizing the elusive goal of being able to target the plethora of mutations in cancer through immunotherapy,” Radvanyi writes.Other cancer researchers agree.”When I saw this paper I thought: “Whoa! I mean, it’s very impressive,” says James Heath, president of the Institute for Systems Biology in Seattle.”One of the most exciting breakthroughs in biomedicine over the past decade has been activating the immune system against various cancers. But they have not been successful in breast cancer. Metastatic breast cancer is basically a death sentence,” Heath says. “And this shows that you can reverse it. It’s a big deal.”One key challenge will be to make the treatment easier, faster, and affordable, Rosenberg says. “We’re working literally around the clock to try to improve the treatment.” Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

The UN expert who told the government that its cut

first_imgThe UN expert who told the government that its cuts to disabled people’s support had caused a “human catastrophe” is to visit the UK this autumn to deliver a high-profile lecture on disability rights.Theresia Degener, the professor of law and disability studies who chairs the UN committee on the rights of persons with disabilities, will deliver the first Caroline Gooding Memorial Lecture at the University of Leeds in October.Last August, Degener (pictured) told the UK government’s delegation – during a public examination of its progress on implementing the UN Convention on the Rights of Persons with Disabilities (CRPD) – that its cuts to social security and other support for disabled people had caused “a human catastrophe” which was “totally neglecting the vulnerable situation people with disabilities find themselves in”.She later gave an interview with the BBC – which was not broadcast – in which she warned that the portrayal of disabled people by the UK government and media as “parasites” who live on benefits could put them at risk of violence, and even “killings and euthanasia”.The annual lecture was set up as a memorial to the equality consultant and author Caroline Gooding, who played a leading role in securing improvements to disability rights legislation as a member of the Disability Rights Taskforce.Gooding was later director of legislative change at the Disability Rights Commission throughout its eight years. She died in July 2014.The lecture will be hosted by the university’s renowned Centre for Disability Studies (CDS) and its Centre for Law and Social Justice, and will take place on 3 October.Professor Anna Lawson, director of CDS and co-ordinator of the university’s Disability Law Hub, said she and fellow organisers were “delighted” that Degener was able to accept the invitation to deliver the lecture.She said: “She is a disabled woman who, like Caroline, has made it her life’s work to push for disability equality and inclusion using the law.“As chair of the CRPD committee, she occupies what is one of the most influential positions in disability rights globally.“The fact that her committee has recently reviewed and made recommendations to the UK on its implementation of the CRPD makes the timing particularly good.“Theresia also knew and admired Caroline and her work.”She said the lecture would not be focused specifically on the UK but would be “relevant to all countries that have ratified the CRPD, including the UK”.Lawson said there would be questions and discussion after the lecture, while there are hopes that the event will be live-streamed.Degener will lecture on “inclusive equality”, a concept introduced by the UN committee through a “general comment” in March and which it hopes can be used to help implement CRPD.Inclusive equality, the general comment says, argues for redistribution to address socioeconomic disadvantage, and attempts to combat “stigma, stereotyping, prejudice and violence” and recognize the “dignity of human beings and their intersectionality”.It also recognises the importance of including different social groups in society, but also the need to “make space for difference as a matter of human dignity”.In the general comment on article five of the convention – on equality and non-discrimination – the committee warns that countries are still approaching disability through charity and medical models, which fail to fully acknowledge disabled people’s rights.It also warns that the laws and policies of many countries “perpetuate the exclusion and isolation of and discrimination and violence” against disabled people, and that they are often “imperfect and incomplete or ineffective” or “reflect an inadequate understanding of the human rights model of disability”.In the BBC interview, Degener explained that, compared to other countries with “less economic power” and less advanced equality and discrimination legislation, the UK’s austerity policy was “less human rights oriented”, so that “UK appears to be a strong country when it comes to equal rights but a very, very weak country with relation to economic, social and culture rights”.She also said the UK’s record on disability rights was “going backwards in a pace and to an amount that it worries us a lot” and that the evidence in front of the committee was “overwhelming”.The general comment also says that disabled people’s organisations (DPOs) must “play a central role in the development of legal and policy reforms”, including the response to the prejudice faced by disabled people seen as being “a burden on society”.The committee’s concluding observations, which followed its public examination of the UK’s progress in implementing the convention last August, called on the government to do more to include DPOs in planning and implementing polices affecting disabled people.Degener was not available this week to comment on her plans for the lecture. A note from the editor:For nine years, Disability News Service has survived largely through the support of a small number of disability organisations – most of them user-led – that have subscribed to its weekly supply of news stories. That support has been incredibly valuable but is no longer enough to keep DNS financially viable. For this reason, please consider making a voluntary financial contribution to support the work of DNS and allow it to continue producing independent, carefully-researched news stories that focus on the lives and rights of disabled people and their user-led organisations. Please do not contribute if you cannot afford to do so, and please remember that DNS is not a charity. It is run and owned by disabled journalist John Pring, and has been from its launch in April 2009. Thank you for anything you can do to support the work of DNS…last_img read more

STARTERS ORDERS Tuesday

first_img[dropcap]W[/dropcap]elcome to Starters Orders. Our daily midday update from the trading room at Star Sports with our key market movers for the day across all sports.Monday 19 JanuaryRACING1.25 SouthwellDubawi Diamond 7/2 > 9/42.30 SouthwellMagical Macey 14/1 > 8/13.35 SouthwellBedloe’s Island 9/2 > 5/2FOOTBALL7.45pm SKY5/2 Liverpool 11/10 Chelsea 12/5 DRAWWhat’s your view?CALL STAR SPORTS ON 08000 521 321last_img