2015 Hurricane Season Forecast as Below Normal

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York Forecasters are predicting the 2015 Atlantic hurricane season will be below normal, but officials urged coastal residents to remain prepared for a storm, the National Oceanic and Atmospheric Administration (NOAA) announced Wednesday.There’s a 70-percent likelihood of between six and 11 named storms with sustained winds of 39 mph or higher, three to six of which could become hurricanes with at least 74 mph winds and two potentially growing into major hurricanes reaching wind speeds of more than 111 mph, NOAA officials said.“Now is the time to start planning before hurricane season starts,” Kathryn Sullivan, NOAA administrator, told reporters during a news conference in New Orleans.Hurricane season runs from June 1 to Nov. 30 and peaks between late August and early September. Sullivan warned that even if the seasonal outlook is below normal, the tropical cyclones that do form will be just as dangerous. The long-term forecast does not predict where exactly the storms may reach landfall.NOAA officials also used the announcement to reminded the public of how to prepare for a storm. Such tactics include stocking enough food and water to last at least 72 hours, discuss a backup plan and meeting places with family, keep important papers in a safe place, avoiding floodwaters and checking on the elderly as well of those with special needs.The biggest reminder is that it’s neither the winds nor rain, but the storm surge associated with hurricanes that can prove most destructive and deadly. Attesting to that was New Orleans Mayor Mitch Landrieu, which still has areas recovering from Hurricane Katrina—the costliest in American history, with Sandy ranking second costliest.“We hope for the best and prepare for the worst,” he said.For more hurricane preparedness tips, visit Ready.Gov for information on preparing an emergency kit. Visit the humanesociety.org for details on how to prepare pets for emergencies, too.last_img read more

Football News Emiliano Sala, Argentine footballer, confirmed dead after cops identify body

first_img For all the Latest Sports News News, Football News News, Download News Nation Android and iOS Mobile Apps. The investigators had recovered a body underwater from the wreckage of a plane carrying the Argentine footballer in the Channel and transported it to the British mainland on Thursday for identification. Britain’s Air Accidents Investigation Branch (AAIB) said that bad weather meant they were unable to recover the plane and as a result it was closing down the operation.The light aircraft was carrying the 28-year-old footballer to his new Premier League team Cardiff City when it disappeared near the British island of Guernsey on January 21, along with 59-year-old pilot David Ibbotson. Sala’s disappearance prompted an outpouring of grief across the footballing world, including at his former club Nantes in France where the plane was flying from.After search operations were suspended, a shipwreck hunter hired by Sala’s family with funds donated by football stars such as Lionel Messi found the wreckage on Sunday. The body was taken to Portland Harbour in southern England on board the Geo Ocean III offshore supply ship.It was then stretchered into a silver van, with Dorset Police confirming it had “left the boat and left the port”, before being taken to a nearby mortuary for identification and a post-mortem. “This morning… the body was brought to Portland Port, Dorset, as this is the nearest part of the British mainland to where the plane was located,” said the police statement.The AAIB, who took over the operation, had on Monday confirmed that an unidentified body had been found at the site. New Delhi: Argentine footballer Emiliano Sala was confirmed dead after the investigators identified the body recovered from the plane wreckage today. According to the Dorset Police, the body brought to UK’s Portland Port has been formally identified by HM Coroner for Dorset as that of professional footballer Emiliano Sala. The families of Sala and the pilot David Ibbotson have been updated with this news and will continue to be supported by specially-trained family liaison officers. Our thoughts remain with them at this difficult time, the police said in a statement. On Monday 21 January 2019 a plane carrying both men was flying from Nantes to Cardiff when it lost contact with Air Traffic Control, north of Guernsey.The news has sent shockwaves in the world of football. Sala’s sister Romina posted a heart-breaking message on Instagram. “Your soul in my soul it will shine forever thus illuminating the time of my existence. I love you, tito,” Romina wrote.last_img read more

Dawson Creek ALS walk to be held Saturday morning

first_imgALS, also known as Lou Gehrig’s Disease, is a terminal condition that destroys the voluntary muscles of the body. Shirley Dubois is the coordinator for the event. She is hoping that people from the northern communities come and take part as the Dawson Creek walk is the only one in the area.“I would like to see more people from up the northern Peace area, because we’re the only walk between Whitehorse, and Prince George,” she says. “The awareness, and the fundraising, is most, most important to us.”Dubois adds that there are no limits to the distance people must walk, or donations they can raise.- Advertisement -Registration will begin at 10 a.m., with the walk beginning at 11.last_img

Genetically engineered immune cells wipe out lupus in mice

first_imgSince CAR-T therapy emerged, scientists who study autoimmune diseases have eyed it with interest because B cells are involved in many of these diseases. B cells can release autoantibodies that damage the body’s tissue and provoke T cells into attacks on tissues as well. In 2016, a team at the University of Pennsylvania reported that mice with a rare autoimmune disease called pemphigus vulgaris were helped by CAR-T therapy.But lupus has presented a puzzle. An antibody called rituximab, which depletes B cells and is often prescribed to patients with rheumatoid arthritis and multiple sclerosis, failed to help many people with lupus in two large clinical trials. That “caused a bit of head-scratching,” says Marko Radic, an immunologist at the University of Tennessee Health Science Center in Memphis.Did the results mean B cells weren’t important in lupus after all? The answer is no, suggests Mark Shlomchik, an immunologist at the University of Pittsburgh in Pennsylvania who was not involved in the new study. He believes rituximab stumbled in part because of an unfortunate confluence of how the antibody works and how the immune system falters in lupus. Rituximab needs immune cells called macrophages to step in and assist in B cell destruction. That works in some diseases, but in lupus, those cells can be “paralyzed,” says Shlomchik, and struggle to pull this off.Enter CAR-T therapy, where T cells become efficient B cell slayers without needing a helping hand. Radic and his colleagues tested the approach in two mouse models of lupus. After the mice got sick, the team exposed them to whole-body radiation to wipe out existing immune cells. (People getting CAR-T therapy receive chemotherapy for the same purpose.) Then, the scientists infused the genetically altered T cells into 41 animals.In 26 of the mice, the CAR-T cells successfully destroyed the B cells with CD19—nearly all of them—and those cells never reappeared. That’s similar to what’s been observed in cancer patients who undergo CAR-T therapy. The effects on mouse health surprised even Radic, who’d had high hopes: The animals’ spleens, skin, kidneys, and other body parts showed no remaining signs of lupus, the team reports today in Science Translational Medicine. “We were so impressed,” Radic says.Most of the animals that were successfully treated lived for more than a year after treatment, a long stretch in mouse-time. Animals that got placebo therapy all died within 8 to 10 months, and many perished earlier.Anolik says she would like to better understand why CAR-T therapy didn’t work for 15 mice. But she’s hopeful for the treatment’s future for her patients and others.The findings are “very compelling,” Shlomchik says. In some patients, lupus is “as aggressive as cancer,” he says, so even a drastic treatment could make sense. Genetically engineered immune cells wipe out lupus in mice Click to view the privacy policy. Required fields are indicated by an asterisk (*) By Jennifer Couzin-FrankelMar. 6, 2019 , 2:00 PM 3D4Medical/Science Source Lupus can be a stubborn disease to treat. Although many struck by the autoimmune condition live relatively normal lives, some suffer from kidney failure, blood clots, and other complications that can be deadly. Now, scientists have found that a novel treatment that wipes out the immune system’s B cells cures mice of the condition. Though the work is preliminary, it has excited researchers because it uses a therapy already approved for people with blood cancer.“This is a critical stepping stone,” says Jennifer Anolik, a rheumatologist who runs the lupus clinic at the University of Rochester Medical Center in New York who was not involved with the work.The strategy is known as chimeric antigen receptor (CAR)-T therapy. It involves genetically engineering T cells, the sentries of the immune system, so they recognize and destroy certain cells in the body. Although it comes with potentially serious side effects, it can be lifesaving. The approach took the cancer world by storm in 2011, after scientists reported saving patients with an advanced form of leukemia. Since then, it has been approved to treat certain leukemias in children and lymphomas in adults. Although CAR-T therapy can target different cells, the approved treatments hunt down and destroy B cells by spotting a protein marker, CD19, that almost all B cells sport on their surface.center_img Sign up for our daily newsletter Get more great content like this delivered right to you! 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